Department of
Biochemistry
Unraveling the Chemistry of Life
The Department of Biochemistry at Bangladesh Medical College (BMC) serves as the cornerstone of molecular medicine, providing comprehensive diagnostic services and advanced research in clinical chemistry, molecular biology, and metabolic disorders. Our expert faculty utilizes state-of-the-art analytical instruments and cutting-edge molecular techniques to deliver precise biochemical analyses essential for disease diagnosis, therapeutic monitoring, and personalized medicine approaches.
Equipped with automated biochemistry analyzers, chromatography systems, molecular diagnostic platforms, and specialized research laboratories, we support clinical decision-making, medical education, and translational research addressing metabolic diseases, nutritional deficiencies, and genetic disorders prevalent in Bangladesh. The department trains MBBS students, postgraduate residents, and laboratory professionals while contributing to national health screening programs and biomarker discovery research.
Clinical Biochemistry Services
- Routine Biochemistry: Complete blood chemistry profiles, liver function tests, renal function tests, lipid profiles, and glucose monitoring.
- Endocrine Testing: Thyroid function tests, reproductive hormones, adrenal function assessment, and diabetes management panels.
- Cardiac Markers: Troponin I/T, CK-MB, BNP, and lipid peroxidation studies for acute coronary syndrome diagnosis.
- Tumor Markers: PSA, CEA, CA-125, AFP, and beta-HCG for cancer screening and monitoring.
- Therapeutic Drug Monitoring: Antiepileptic drugs, immunosuppressants, antibiotics, and chemotherapy drug levels.
- Electrolyte & Acid-Base Analysis: Comprehensive electrolyte panels, arterial blood gas analysis, and anion gap calculations.
We provide 24/7 emergency biochemistry services with rapid turnaround times and maintain strict quality control standards for accurate clinical interpretation.
Advanced Analytical Technologies
- Fully Automated Analyzers: High-throughput chemistry analyzers, immunoassay systems, and hematology analyzers with barcode technology.
- Chromatography: HPLC, GC-MS for drug analysis, amino acid profiling, and organic acidurias.
- Molecular Diagnostics: Real-time PCR, DNA sequencing, and gene expression analysis for genetic disorders.
- Spectrophotometry: UV-Vis, fluorescence spectroscopy for enzyme kinetics and protein quantification.
- Electrophoresis: Serum protein electrophoresis, hemoglobin electrophoresis, and DNA fragment analysis.
- Mass Spectrometry: LC-MS/MS for vitamin D, steroid hormones, and metabolic profiling.
Our laboratory is equipped with LIS (Laboratory Information System) integration and maintains NABL accreditation with participation in international proficiency testing programs.
Specialized Testing & Research Areas
- Metabolic Disorders: Inborn errors of metabolism, lysosomal storage diseases, and mitochondrial disorders screening.
- Nutritional Biochemistry: Vitamin profiles, trace elements, amino acid analysis, and malnutrition biomarkers.
- Toxicology Screening: Heavy metals, pesticides, drug overdose panels, and environmental toxin analysis.
- Reproductive Endocrinology: Infertility workup, PCOS profiling, and menstrual disorder investigations.
- Diabetes Research: Glycation studies, insulin resistance markers, and diabetic complications monitoring.
- Cancer Biochemistry: Oxidative stress markers, proteomic profiling, and chemotherapy response monitoring.
The department focuses on region-specific metabolic and nutritional disorders through collaborative research with clinical specialties and public health programs.
Molecular Biology & Genetics
- PCR-based genetic testing for thalassemia, sickle cell anemia, and hereditary cancers
- DNA extraction and quantification from various clinical samples
- Gene mutation analysis and carrier screening programs
- Flow cytometry for immunophenotyping and cell cycle analysis
- RNA extraction and RT-PCR for viral load quantification
- Biomarker discovery using proteomic and metabolomic approaches
We provide genetic counseling support and collaborate with clinical genetics for comprehensive patient management of hereditary disorders.
Quality Assurance & Accreditation
- Internal quality control programs with daily calibration and validation
- External quality assessment schemes (EQAS) participation
- NABL accreditation and ISO 15189 compliance
- Standard operating procedures (SOPs) for all analytical methods
- Proficiency testing in clinical chemistry and molecular diagnostics
- Bio-safety level 2 (BSL-2) laboratory practices
Our quality management system ensures reliable test results and compliance with international laboratory standards.
Educational Programs & Training
- MBBS curriculum in clinical biochemistry and molecular biology
- MD Biochemistry postgraduate residency training
- Diploma in Medical Laboratory Technology (DMLT)
- Workshops on HPLC, mass spectrometry, and molecular techniques
- Short courses in quality management and laboratory accreditation
- Research methodology training for biomedical scientists
The department serves as a regional training center for advanced biochemical techniques and laboratory management practices.
Research & Community Health Contributions
- Population-based screening for metabolic syndrome and diabetes
- Nutritional assessment programs for maternal and child health
- Thalassemia carrier screening and premarital counseling
- Environmental toxicology studies and heavy metal exposure assessment
- Biomarker research for tropical diseases and infections
- Development of point-of-care testing for rural healthcare
We collaborate with national health programs for disease surveillance, reference laboratory services, and development of cost-effective diagnostic solutions.
